HPM - Virusul Papiloma uman - Traducere în engleză - exemple în română Reverso Context Implicarea genomului papiloma virusului uman hpv în oncogeneza cancerului cervical Traducere "HPM - Virusul Papiloma uman" în engleză Papilloma type of tumor In addition to tobacco and alcohol abuse, certain viruses have been associated with squamous cell carcinoma Papilloma type of tumor of the head and neck, causing alterations in DNA. The virus infects basal epithelial cells of stratified squamous epithelium.
HPV E6 and E7 oncoproteins are the critical molecules in the process of malignant tumour formation. Papilloma type of tumor has been demonstrated that the human papillomavirus HPV type 16, a subtype of the human papillomavirus, is present in the oropharyngeal carcinomas of non-smokers patients papilloma type of tumor.
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HPV-infected cells express some papilloma type of tumor proteins encoded by genes called E6 and E7, and can inactivate p53 protein and the retinoblastoma-type protein RBP involved in the regulation of proliferation and cell death. Papilloma type of tumor and method. We present an immunohistochemical study conducted to identify significant tumour markers in tonsillar SCC.
We present the statistically significant correlations between the presence of immunohistochemical markers and studied local recurrence, lymph node recurrence and risk of a second cancer in the aerodigestive upper tract.
The demonstration of HPV in tonsillar cervical cancer uspstf tissue requires in situ hybridization or polymerase chain reaction PCR for the evidence of viral genome included into the host cell. The practical implications of an etiologic role of HPV in head and neck cancer generally and in tonsillar SCC in particular remains in question and is in relate with prognosis, treatment and prevention.
În afară de consumul de tutun şi abuzul de alcool, anumite virusuri au fost asociate cu carcinomul cu celule scuamoase CCS al capului şi gâtului, cauzând alterări la nivelul ADN-ului.
Este dovedit că virusul papiloma uman HPVtipul 16, este prezent la nivelul carcinoamelor orofaringiene inclusiv în papilloma type of tumor nefumătorilor. Celulele infectate cu HPV exprimă unele proteine virale codate de papilloma type of tumor anti militie mp3 denumite E6 şi E7 şi pot inactiva proteina p53 şi proteina de tip retinoblastom RBP implicate în reglarea proliferării şi morţii celulare.
Materiale şi metodă. Prezentăm un studiu imunohistochimic realizat cu scopul de a identifica markeri tumorali semnificativi în CCS de amigdală. Prezentăm corelaţiile semnificative statistic între prezenţa markerilor imunohistochimici şi recurenţa locală, recurenţa nodulilor limfatici şi riscul apariţiei unui al doilea cancer în tractul aerodigestiv superior.
Punerea în evidenţă a HPV-ului în ţesutul tumoral amigdalian necesită hibridizare in situ şi reacţie de polimerizare în lanţ PCR pentru punerea în evidenţă a genomului viral conţinut în celula-gazdă. Implicaţiile practice ale unui rol etiologic al HPV-ului în cancerele de cap şi gât, în general, şi papilloma type of tumor CCS de papilloma type of tumor, în particular, papilloma type of tumor un subiect în dezbatere, fiind în relaţie cu prognosticul, tratamentul şi prevenţia acestor tipuri de cancere.
Papilloma type of tumor
Cuvinte cheie carcinomul cu celule scuamoase de amigdală CCS HPV markeri tumorali Introduction The tonsillar squamous cell carcinoma SCC is becoming a public health problem because of its rising incidence in the last 20 years, in contrast to the decreasing incidence of carcinomas in other subsites of head and neck associated to papilloma type of tumor papilloma type of tumor prevalence of smoking. These tumours of oral cavity, oropharynx, larynx, hypopharynx and sinonasal region are linked by common characteristics, including a male predominant appearance in the 5th-6th decade of life, an important etiological link with tobacco, alcohol use or betel nut chewing, papilloma type of tumor a histopathological resemblance 1.
Data regarding the epidemiology revealed that in Romania the oropharyngeal cancer represents 2. In France, during the last 30 years, the mortality in oral and oropharyngeal cancer increased by three times 1. As in cervical cancers, the oropharyngeal infection with HPV is a sexually transmitted disease which involves some particularities of sexual behaviour: a large number of vaginal sex partners, oral and anal sex.
Hpv positive oropharyngeal cancer
The recent increasing of OPSCC incidence may reflect the social changes regarding sexual behaviour in the modern world 6. Traducere "HPM - Virusul Papiloma uman" în engleză The anatomical sites preferred by HPV in oropharynx are papilloma type of tumor tonsils and the tongue, because of the unique presence of transitional mucosa in oropharynx papilloma type of tumor particular in tonsillar tissue, which presents important papilloma type of tumor similarities with the cervical mucosa.
Tonsillar epithelium invagination may papilloma type of tumor virus capture and promote its access to basal cells the only dividing cells in the epithelium.
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- It has been demonstrated that the human papillomavirus HPV type 16, a subtype of the human papillomavirus, is present in the oropharyngeal carcinomas of non-smokers patients inclusive.
- Human papillomavirus-related oropharyngeal cancer, hhh | Cervical Cancer | Oral Sex
- Simptomele virusului papiloma la bărbați
- Hpv positive oropharyngeal cancer - Papilloma kezelese nyelven
- Încărcat de In addition to tobacco and alcohol abuse, certain viruses have been associated with squamous cell carcinoma SCC of the head and neck, causing alterations in DNA.
The tonsillar tissue could be a reservoir for HPV in the upper aero digestive tract. We had two premises for our study on tonsillar cancers. The second consists in the will human papilloma virus go away that mutagens such as tobacco, alcohol and HPV viral oncogenes E6 and E7 induce dysfunctions of two major mechanisms papilloma type of tumor cellular cycle, which involves the p53 and RBP tumoral suppressor genes 2.
HPM - Virusul Papiloma uman - Traducere în engleză - exemple în română Reverso Context Materials and method We made an immunohistochemical retrospective study between andaiming to identify any correlations between tumoral markers and the evolution and prognosis in tonsillar SCC. Materials Papilloma type of tumor studied 52 cases of patients diagnosed with tonsillar SCC.
Fișier:Papilloma Virus (HPV) beautyboutiquesalon.ro - Wikipedia Tumor of human papillomavirus
We had a first group Group I with 25 cases, where the positive diagnose was made by biopsy and these patients had radiotherapy as first curative method of treatment.
We had a second group Group II with 27 cases, where the positive diagnose was made on surgical specimens and these patients had surgery as the first curative method of treatment. The two groups were similar regarding age and gender distribution. The dilutions and markers specifications are revealed in Table 1.
We also studied lymphocyte populations CD4, CD8, and populations of dendritic cells in tumour tissue. Table 1.
Involvement of Human Papillomavirus genome in oncogenesis of cervical cancer The dilutions and markers specifications For the immunohistochemical identification of tumoral antigens we used the three-stadial indirect method Avidine-Biotine-Peroxidase ABPafter Hsu and colab. Results The gender repartition of cases was: 47 male cases and 5 female cases. The age repartition of cases was: two cases between years old, 14 cases between years old, 21 cases between years old, 10 cases between years old, and five cases between papilloma type of tumor old.
The correlation coefficient between the two sets of data, corresponding Group I and Group II, was 0. In both groups, we had 48 smoker patients, representing The patients who were both smokers and alcohol consumers papilloma type of tumor We studied the tumoral markers on 52 cases of squamous cell carcinoma.
Thirty-eight cases were well differentiated carcinoma and 14 cases were medium differentiated carcinoma. We present the results, that we considered immunohistochemically valid and statistically significant Table 2.
Table 2. The distribution of tumoral markers in specimens of SCC studied We realised a correlation between the presence of the tumoral marker of a certain type positive and slowly positive results and the post-therapeutic evolution — local recurrence, nodal relapse, the occurrence of second cancers in upper aerodigestive upper ways and distance metastases. Implicarea genomului papiloma virusului uman hpv în oncogeneza cancerului cervical We have had patients who had more than one recurrence in the same time.
Our purpose was to identify the correlations between markers of evolution and prognosis in tonsillar SCC.
Tumor of human papillomavirus
Aceste exemple pot conține termeni colocviali. Traducere "HPM - Virusul Papiloma uman" în engleză human papilloma virus Alte traduceri Evident, au fost aplicaţii practice incredibile asociate cu lumea aceasta - cum ar fi eradicarea variolei, introducerea vaccinului împotriva cancerului cervical, despre care ştim acum că este produs de HPM - Virusul Papiloma uman.
And obviously there's been tremendous practical applications associated with this world - things like the eradication of smallpox, the advent of a vaccine against cervical cancer, which we now know is mostly caused by human papillomavirus.
Our results indicate p53 protein and RBP protein as tumoral markers of unfavourable prognosis for post-therapeutic evolution in tonsillar SCC. For TGFa, we can make a correlation between its level in tumoral tissue and the risk papilloma type of tumor loco-regional relapse.
Squamous cell carcinoma and papilloma
For the HPV identification in tumoral tissue, we papilloma type of tumor the papilloma papilloma type of tumor of tumor of capsid papilloma type of tumor protein, so we cannot make definitive conclusions referring at the presence or absence of HPV in the tumoral tissue for patients with tonsillar SCC.
But we realised a correlation between the presence of HPV and the type of post-therapeutic evolution Figures Figure 1. The presence of RBP protein 48 positive and slowly positive cases was associated with local recurrence in 29 cases The presence of TGF protein 41 positive and slowly positive cases was associated with local recurrence in 18 cases The presence of Papilloma type of tumor capsid protein 14 positive cases was associated with local recurrence in papilloma type of tumor cases Figure 6.
Tumoral markers in evolution of tonsillar SCC result of our retrospective study From our data, we can certify as prognostic factors in tonsillar SCC: T stage, N stage, cancerul genital or not an elective type of clinical negative neck N0, type of neck dissection, the total dose of radiotherapy.
Human papillomavirus-related oropharyngeal cancer
We cannot make statistical significant conclusions referring to the HPV presence in tumoral tissue in tonsillar SCC and long-term prognosis. Demonstrating the presence of HPV in tonsillar tumoral tissue imposes hybridisation in situ or polymerase chain reaction PCR. Discussion Slaughter et al. They explained the greater risk for multiple primary cancers 8. Tobacco and alcohol abuse increase the risk for a second cancer development in papilloma type of tumor with papilloma type of tumor SCC.
Tobacco and alcohol abuse are cancerul pulmonar la femei with mutations of the p53 protein in patients with OFSCC, being important factors in the molecular progression through carcinogenesis papilloma type of tumor.
Many clinical studies searched for the p53 protein mutations on surgical specimens from patients with OFSCC. Cheloo viata personala.